Fig. 3: Current source density profile and field potential generators of δ-oscillations during SDs.
From: Diversity of cortical activity changes beyond depression during Spreading Depolarizations
a Example traces of FP (black) at different cortical depths overlaid on current-source density (CSD) map in pre-SD epoch (left), during full SD (middle) and partial SD terminated at depth of 1200 μm (right). b Average UP-states of δ-oscillations during pre-SD epoch and partial SD (left), and corresponding CSD values at the peak of the UP-states (right). c Example traces of the four main FP generators obtained by the independent component analysis (ICA) of FP profiles. d Left, Characteristic spatial profile (left) of each component of the FP generator (Main (blue), L3 (green), L5/6 (red) and Remote (purple)). Right, the second derivative of the spatial profiles (right) as an analog of CSD. e The time course of each of the generators during a full SD (left) and partial SD (right) stopped at a depth of 1200μm. f Grouped data from 11 rats (n = 180 SDs) presented as boxplots [center line, median; edges, Q1/Q3; whiskers, non-outlier extremes] for the SD/pre-SD power ratio (values < 1 correspond to a depression, >1 refers to a boom) for each of the generators at three ranges of SD stop depth: less than 1 mm (surface Partial SDs), between 1 and 1.5 mm (intermediate Partial SDs), and deeper than 1.5 mm (Full SDs), Kruskal-Wallis test. Source data are provided as a Source Data file.
