Fig. 1: Mb reaction with benzyl diazoketone. | Nature Communications

Fig. 1: Mb reaction with benzyl diazoketone.

From: Mechanistic manifold in a hemoprotein-catalyzed cyclopropanation reaction with diazoketone

Fig. 1: Mb reaction with benzyl diazoketone.The alt text for this image may have been generated using AI.

a Mb(H64G,V68A)-catalyzed cyclopropanation of styrene with benzyl diazoketone (BDK) and substrate scope of the biocatalyst (box; R = aryl or alkyl; R’ = H or Me). b Color change of a Mb(H64G,V68A) solution upon addition of BDK (box) and corresponding transition in the UV-Vis absorption spectrum (2 mM Mb(H64G,V68A)) in 50 mM sodium borate buffer (NaBB) (pH 9.0), anaerobic conditions, before (red curve) and after (green curve) addition of BDK.

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