Table 1 Participants’ characteristics of UK Biobank
From: Plasma proteomic profiles predict individual future health risk
Participants characteristics | All participants (N = 52,006) | Female (N = 28,056) | Male (N = 23,950) |
|---|---|---|---|
Demographic | |||
Age | 58 [50–64] | 58 [50–63] | 59 [50–64] |
Ethnicity (white) | 48,517 (93.7%) | 26,204 (93.8%) | 22,313 (93.7%) |
Townsend deprivation index | −2.1 [−3.6 to 0.8] | −2.1 [−3.6 to 0.7] | −2.1 [−3.6 to 0.9] |
Education, years | 11 [10–15] | 11 [10–15] | 11 [10–15] |
Lifestyle | |||
Current smoker | 5481 (10.6%) | 2492 (8.9%) | 2989 (12.5%) |
Frequent alcohol intake | 35,615 (68.6%) | 17,248 (61.6%) | 18,367 (76.9%) |
Regular activity | 39,548 (78.0%) | 21,094 (77.2%) | 18,454 (78.9%) |
Physical measures | |||
Body mass index | 26.8 [24.2–29.9] | 26.2 [23.5–29.8] | 27.3 [25.0–30.0] |
Basal metabolic rate, kj | 6360 [5489–7581] | 5552 [5184–6000] | 7657 [7037–8355] |
Systolic blood pressure, mmHg | 138 [126–152] | 135 [122–150] | 141 [130–154] |
Disease and medication history | |||
History of diabetes | 2948 (5.7%) | 1098 (3.9%) | 1850 (7.7%) |
History of hypertension | 14,605 (28.1%) | 6745 (24.0%) | 7860 (32.8%) |
Cholesterol medications | 9678 (18.9%) | 3747 (13.5%) | 5931 (25.2%) |
Family disease history | |||
Parents’ history of diabetes (single) | 7565 (16.7%) | 4293 (17.2%) | 3272 (16.1%) |
Parents’ history of diabetes (both) | 603 (1.3%) | 319 (1.3%) | 284 (1.4%) |
Parents’ history of dementia (single) | 5421 (12.0%) | 3132 (12.6%) | 2289 (11.2%) |
Parents’ history of dementia (both) | 222 (0.5%) | 121 (0.5%) | 101 (0.5%) |
Serum | |||
HDL cholesterol, mmol/L | 1.4 [1.2–1.7] | 1.5 [1.3–1.8] | 1.2 [1.1–1.4] |
Triglycerides, mmol/L | 1.5 [1.0–2.1] | 1.3 [1.0–1.9] | 1.7 [1.2–2.4] |
Glucose, mmol/L | 4.9 [4.6–5.3] | 4.9 [4.6–5.3] | 5.0 [4.6–5.4] |
HbA1c, mmol/mol | 35.3 [32.9–38.1] | 35.3 [32.9–37.9] | 35.4 [32.8–38.3] |
IGF-1, nmol/L | 21.2 [17.4–24.7] | 20.6 [16.8–24.4] | 21.7 [18.1–25.1] |
Alanine aminotransferase, U/L | 20.0 [15.3–27.1] | 17.5 [13.9–22.8] | 23.4 [18.2–31.4] |
Albumin, g/L | 45.1 [43.4–46.9] | 44.9 [43.2–46.6] | 45.4 [43.7–47.2] |
Creatinine, umol/L | 70.7 [61.4–81.4] | 63.2 [57.0–70.5] | 80.2 [72.6–88.9] |
Leukocyte count, 109 cells/L | 6.6 [5.6–7.9] | 6.6 [5.6–7.8] | 6.7 [5.6–7.9] |
Erythrocyte count, 1012 cells/L | 4.5 [4.2–4.8] | 4.3 [4.1–4.5] | 4.7 [4.5–5.0] |
Platelet count, 109 cells/L | 248.0 [213.0–287.0] | 261.0 [225.2–300.0] | 233.2 [201.0–269.0] |
