Fig. 1: Excessive fructose intake reduces liver manganese content.
From: Fructose overconsumption impairs hepatic manganese homeostasis and ammonia disposal
a–c C57BL/6 J male mice at the age of 2 months were fed normal chow diet (NCD) or a conventional high fructose diet (HFR, 65% fructose, Research Diets) for 2 weeks or 8 weeks (n = 6). Their Mn levels in the plasma (a), liver (b), and bile (c). d-h C57BL/6 J male mice at the age of 2 months were fed 60% starch diet (starch) or 60% fructose diet (fructose) for 1 week (n = 5). Food Mn contents (d), dietary Mn intake (e), Mn contents in the plasma (f), liver (g), and bile (h). Data represent means ± SEM. Two-tailed unpaired Student’s t-test. Source data are provided as a Source Data file.
