Table 1 Summary of major genes under selection in indicine cattle

From: Global genetic diversity, introgression, and evolutionary adaptation of indicine cattle revealed by whole genome sequencing

BTA

Region (Mb)

FST

θπ

XP-EHH

Gene identified

Association

Reference

1

81.58–81.69

0.74

0.23

3.42

LIPH

Hair development

21

7

43.18–43.29

0.69

0.49

2.62

FGF22

Hair development

79

7

50.14–50.31

0.83

0.57

0.78

LRRTM2, CTNNA1, SIL1, MZB1, PROB1, PAIP2, SLC23A1

Brain development, muscle development, antiviral immunity, reproduction, vitamin C transporters

5

7

50.64–51.15

0.84

0.58

2.26

SPATA24, DNAJC18, TMEM173, UBE2D2, ECSCR, CXXC5, PSD2, NRG2

Fertility, reproduction, heat stress

5

8

53.22–53.27

0.64

0.32

2.64

VPS13A

Blood circulation

80

16

50.50–50.67

0.74

0.22

3.02

PRKCZ, FAAP20

Light response, DNA damage

81, 82

19

26.38–26.45

0.72

0.34

3.62

SPAG7, PFN1, KIF1C, CAMTA2, ENO3

Antiviral immunity, skeletal development, neurodegenerative disease, cardiac growth, muscle development,

16,17,18, 20, 83,19

19

27.40–27.61

0.74

0.94

2.96

WRAP53, TMEM88

DNA damage, heart development

84, 85

22

55.80–55.85

0.64

0.15

2.20

TAMM41

Heart valve development

86