Fig. 1: 19F labeling of βarr1 for NMR experiments.
From: Distinct activation mechanisms of β-arrestin-1 revealed by 19F NMR spectroscopy
a Selected residues for 19F labeling in the inactive βarr1 crystal structure (PDB: 1JSY). Residues in different structural regions are shown in different colors. b Schematic illustration of the key structural regions associated with βarr1 activation using the same color coding as in a. The middle region of CT is shown as ribbon colored in blue, whereas the proximal and distal regions unobservable in the crystal structure are shown as blue dashed lines. c Illustration of the different functional states of βarr1 examined in this study.
