Fig. 6: Possible cross-talk between PIP2 and V2Rpp binding.
From: Distinct activation mechanisms of β-arrestin-1 revealed by 19F NMR spectroscopy

a 19F NMR spectra of labeling sites in the central crest or C-domain showing the effects of simultaneous addition of V2Rpp and PIP2. b Comparison of the 19F CEST profiles and 1D 19F spectra of the E206C site in the ΔCT construct in the presence or absence of PIP2.