Fig. 2: Omicron BA.2.86 infection in cell culture.
From: Evolution and neutralization escape of the SARS-CoV-2 BA.2.86 subvariant
A Foci formed by ancestral D614G, XBB.1.5, and BA.2.86 20 h post-infection on Vero-TMPRSS2 cells (rows 1, 3, 5) and cytopathic effect by the same viral inoculum at 72 h post-infection (rows 2, 4, 6). Rows 1 and 2 were infected with D614G, 3 and 4 with XBB.1.5, and 5 and 6 with BA.2.86. The number of foci per well is indicated above each well. B Quantitation of focus area for D614G, XBB.1.5, and BA.2.86 in Vero-TMPRSS2 cells. Bars are geometric means of focus area (n = 1389 for D614G, n = 1049 for XBB.1.5, n = 720 for BA.2.86) from three independent experiments. C Quantitation of focus area for D614G, XBB.1.5, and BA.2.86 in H1299-ACE2 cells. Bars are geometric means of focus area (n = 5016 for D614G, n = 5584 for XBB.1.5, n = 4921 for BA.2.86) from three independent experiments. Significant p-values were *p = 0.02, ****p < 10−15 by the two-sided Kruskal–Wallis test with Dunn multiple hypothesis correction.
