Fig. 4: Application in enantioselective arylalkylation of nonactivated alkenes.
From: Nickel/photoredox dual catalyzed arylalkylation of nonactivated alkenes
Reaction conditions: nonactivated alkenes (0.20 mmol), α-amino acids (0.40 mmol), photocatalyst (0.004 mmol), nickel catalyst (0.04 mmol), L1 (0.044 mmol), base (0.33 mmol), and MgCl2 (0.05 mmol) in 2.0 mL MeCN, were placed at approximately 8.0 cm away from two parallel LEDs (Blue LEDs, 455 nm, 18 W), and were heated at 40 °C in an oil bath for 48 h. [a] Without MgCl2. 4CzIPN, 2,4,5,6-tetra(9H-carbazol-9-yl)−1,3-benzenedicarbonitrile.
