Fig. 2: Phylogenetic analysis of convergent, MDR-cKP, NON-MDR-cKp, and hvKP isolates.

A core genome phylogenetic tree of convergent isolates along with representative isolates of MDR-cKP, NON-MDR-cKp, and hvKP groups was generated. The presence of ST, KL type, virulence genes, and ESBL or carbapenemase genes are indicated. Two well-characterized hvKP reference strains are included: NTUH-K2044 and KPPR1. iuc  =  aerobactin biosynthesis genes, iro  =  salmochelin biosynthesis genes, ybt  =  yersiniabactin biosynthesis loci, clb  =  colibactin biosynthesis loci, rmpADC  =  mucoid regulator operon, rmpA2 = mucoid regulator 2 gene, ESBL = extended-spectrum beta-lactamase gene, CPE = carbapenemase producing Enterobacteriaceae.