Fig. 8: Transcriptomics analyses of PD mice with or without Ptzyme@D-ZIF therapy. | Nature Communications

Fig. 8: Transcriptomics analyses of PD mice with or without Ptzyme@D-ZIF therapy.

From: Chiral metal-organic frameworks incorporating nanozymes as neuroinflammation inhibitors for managing Parkinson’s disease

Fig. 8: Transcriptomics analyses of PD mice with or without Ptzyme@D-ZIF therapy.The alternative text for this image may have been generated using AI.

A Venn diagram of transcriptomic profiles on PD mice with or without Ptzyme@D-ZIF treatment. B Volcano plots illustrate the dramatically differentially expressed genes (DEGs) after treatment with Ptzyme@D-ZIF. (C) GO enrichment and (D) KEGG pathway enrichment analysis of the identified DEGs, which show the 20 most remarkably enriched pathways. The rectangular box circled the enriched target signaling pathways. Heat maps of dramatically (E) downregulated and (F) upregulated genes for the analysis of ferroptosis.

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