Fig. 5: (GGGGCC)10 aggregation in presence of 10 µM PDS. | Nature Communications

Fig. 5: (GGGGCC)10 aggregation in presence of 10 µM PDS.

From: The ALS/FTD-related C9orf72 hexanucleotide repeat expansion forms RNA condensates through multimolecular G-quadruplexes

Fig. 5

(GGGGCC)10 was annealed at 150 µM under mG4-forming conditions. The sample containing the G4-ligand presents less aggregates and of a smaller size with respect to the non-PDS containing controls. 100 µm scalebar. The micrographs are representative micrographs of n = 2 independent experiments.

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