Fig. 5: Effect of cholesterol dynamics on membrane bending modulus.
From: Nonuniversal impact of cholesterol on membranes mobility, curvature sensing and elasticity
The bending modulus was analyzed for DPPC (a) and DOPC bilayers (b) based on unperturbed coarse-grained MD simulations in the absence of cholesterol (gray bars), in presence of 40% cholesterol, with blocked cholesterol flipping between the layers (noflip), and for simulations with blocked cholesterol flipping and restrained lateral cholesterol diffusion (restr.). Displayed are mean values and errors as 95% confidence intervals employing parametric bootstrapping (N = 50,000 statistically independent samples) assuming Gaussian distributions of the mode-dependent amplitudes78.
