Fig. 2: Lag-response curves for the relative risks of neurodegenerative disease death comparing extreme high temperatures (the 97.5th percentile, A) and extreme low temperatures (the 2.5th percentile, B) to the minimum-death temperatures, at the national and regional levels.

The lines represent the point estimates, and the shadings indicate corresponding 95% confidence intervals. The results for other climatic zones were not presented due to the null associations. Source data are provided as a Source Data file.