Fig. 6: CsA withdrawal restores recipient T cell rejection against IRU CAR-T cells. | Nature Communications

Fig. 6: CsA withdrawal restores recipient T cell rejection against IRU CAR-T cells.

From: Cyclosporine A-resistant CAR-T cells mediate antitumour immunity in the presence of allogeneic cells

Fig. 6: CsA withdrawal restores recipient T cell rejection against IRU CAR-T cells.The alternative text for this image may have been generated using AI.

a Schematic of ALL mouse model with rechallenged RTCs for (b). b Frequencies of donor CAR-T (left) and recipient T cells (right) in bone marrow at day 14 and 21 (n = 10 and 11 animals in three batches at day 14 and 21 respectively in each group). All data are means±s.d, P values were determined by two-tailed unpaired t test (b). IRU CAR-T (+CsA-CsA) as purple circle, IRU CAR-T (+CsA+CsA) as green rhombus.

Back to article page