Fig. 5: Applying GSDensity to reveal spatial relevant molecular programs in mouse anterior brain.
From: Pathway centric analysis for single-cell RNA-seq and spatial transcriptomics data with GSDensity
a UMAP visualization of 15 cell clusters in the mouse anterior brain dataset. b Visualization of the 15 cell clusters in the spatial map. c Visualization of 727 gene ontology (biological process) terms based on their cluster-wise specificity and spatial relevance. The gene ontology terms are the ones having significant coordination in the mouse anterior brain dataset (Methods). The data points highlighted with red represent the ones with high cluster-wise specificity. The data points highlighted with blue represent the ones with low cluster-wise specificity and high spatial relevance. Source data are provided as a Source Data file. d–g Examples of gene sets with high cluster-wise specificity. h–k Examples of gene sets with low cluster-wise specificity but high spatial relevance.
