Fig. 2: MS-based serum proteomic analysis of discovery cohort. | Nature Communications

Fig. 2: MS-based serum proteomic analysis of discovery cohort.

From: Proteomics-driven noninvasive screening of circulating serum protein panels for the early diagnosis of hepatocellular carcinoma

Fig. 2

a Overview of serum proteomics by DIA-MS. b Comparison of the number of proteins identified in the serum proteome and the spectral library. c Number of proteins identified and quantified with a 1% FDR in four groups (AsC, n = 40 biologically independent samples; BLD, n = 64 biologically independent samples; LC, n = 53 biologically independent samples; HCC, n = 163 biologically independent samples). Data represent mean ± SD. d Proteins identified in the 4 groups were ranked according to their median intensity. The top ten most abundant proteins are labeled, and their relative contribution to the total protein intensity is indicated. Source data are provided as a Source Data file.

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