Fig. 6: Known AMR genes predictive of resistance in antibiotic models.

a Undirected graph of genes found by ML as predictive of resistance-susceptibility profiles to a panel of 21 antimicrobials in E. coli and present in public AMR gene databases connected to the antibiotic model in which they were selected. Nodes of the graph represent either the antibiotic model (indicated by three letter antibiotic abbreviation) or the known AMR gene. Gene nodes are colour-coded by antibiotic class. Edges of graphs connect antibiotic model nodes to gene nodes and are unweighted. b Undirected graph of genes found by ML as predictive of resistance-susceptibility profiles to a panel of 12 antimicrobials in S. enterica and present in public AMR gene databases connected to the antibiotic model in which they were selected. Nodes of the graph represent either the antibiotic model (indicated by three letter antibiotic abbreviation) or the known AMR gene. Gene nodes are colour-coded by antibiotic class. Edges of graphs connect antibiotic model nodes to gene nodes and are unweighted.