Fig. 1: Cryo-EM structures of ELIC in different nanodiscs.
From: Lipid nanodisc scaffold and size alter the structure of a pentameric ligand-gated ion channel
Each structure is named according to whether agonist is absent (apo) or present (no label), followed by the type of scaffold used, followed by the ion channel protein (ELIC or ELIC5) in subscript. The colors used for each structure from PyMOL 2.5.2 are: raspberry for apo-MSP1E3D1ELIC, light blue for apo-spMSP1D1ELIC, deep purple for MSP1E3D1ELIC5, pale yellow for spNW15ELIC5, cyan for MSP1E3D1ELIC, lime green for SMAELIC, deep olive for saposinELIC, gray for spMSP1D1ELIC, and orange for spNW15ELIC. Apo-MSP1E3D1ELIC is EMD-27217, MSP1E3D1ELIC is EMD-27218, and MSP1E3D1ELIC5 is EMD-27220. ELIC and ELIC5 densities are shown using the sharpened cryo-EM maps, and the nanodisc density is shown using the unsharpened maps low-pass filtered at 8 Å.
