Fig. 3: The ratiometric imaging of Ir-NP in vitro. | Nature Communications

Fig. 3: The ratiometric imaging of Ir-NP in vitro.

From: A light-activatable theranostic combination for ratiometric hypoxia imaging and oxygen-deprived drug activity enhancement

Fig. 3

a, b Luminescent imaging and ratio-metric results of Ir-NP with 4T1 cells after different incubation time. Ratio = Ch1 (650–700 nm) / Ch2 (750 – 800 nm). The statistical data are expressed as mean values  ±  S.D. (n = 15 independent experiments). c, d Luminescent imaging and ratio-metric results of Ir-NP with different cells after same incubation time. Ratio = Ch1 (650–700 nm)/Ch2 (750–800 nm). ***P  <  0.0001 (Bend.3 vs 4T1), ***P  <  0.0001 (4T1 vs H22). One-way ANOVA with Dunnett’s multiple comparisons test. The statistical data are expressed as mean values  ±  S.D. (n = 34 independent experiments). The term (arb. units) is abbreviated for arbitrary units.

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