Fig. 2: MN or HI Antibody responses to egg- and cell-propagated vaccine viruses at pre-vaccination (Day 0), 1-month, and 6-months post-vaccination in Year 1. | Nature Communications

Fig. 2: MN or HI Antibody responses to egg- and cell-propagated vaccine viruses at pre-vaccination (Day 0), 1-month, and 6-months post-vaccination in Year 1.

From: Redirecting antibody responses from egg-adapted epitopes following repeat vaccination with recombinant or cell culture-based versus egg-based influenza vaccines

Fig. 2: MN or HI Antibody responses to egg- and cell-propagated vaccine viruses at pre-vaccination (Day 0), 1-month, and 6-months post-vaccination in Year 1.

Antibody titers from each of the four vaccine groups were presented as geometric mean titers (GMTs) with 95% confidence interval (CI) respectively for 18−44 years and 45−64 years age groups. Gray dots represented individual titers. Fluzone IIV4 18−44 years: Day 0 (n = 52), 1 m (n = 52), 6 m (n = 47); Fluzone IIV4 45-64 years: Day 0 (n = 58), 1 m (n = 58), 6 m (n = 54); Fluarix IIV4 18−44 years: Day 0 (n = 55), 1 m (n = 55), 6 m (n = 48); Fluarix IIV4 45−64 years: Day 0 (n = 65), 1 m (n = 63), 6 m (n = 59); ccIIV4 18−44 years: Day 0 (n = 135), 1 m (n = 133), 6 m (n = 124); ccIIV4 45−64 years: Day 0 (n = 148), 1 m (n = 147), 6 m (n = 142); RIV4 18−44 years: Day 0 (n = 99), 1 m (n = 98), 6 m (n = 85); RIV4 45−64 years: Day 0 (n = 98), 1 m (n = 98), 6 m (n = 92); Microneutralization titers (MN) were measured for A(H3N2) virus, while hemagglutination inhibition (HI) titers were measured for A(H1N1)pdm09, B/Victoria (B/VIC), and B/Yamagata (B/YAM) viruses. One-way ANOVA corrected for multiple comparisons (Tukey’s test) was used to compare the GMTs of each time point among the 4 vaccine groups. Statistically significant differences between groups are indicated by p values on the horizontal bars.

Back to article page