Fig. 2: Expression changes over branches and tissues.

A Expression changes inferred across species for the five tissues and sexes. The number above each branch is the total number of expression changes (up and down), and the thickness of the branch is proportional to that number. B Quantification of the genes that change in expression across multiple tissues. The height of each bar indicates the number of genes that have changed expression across the set of tissues indicated by the darkened/colored circles. C Schematic illustrating a hypothetical gene X having expression changes involving multiple tissues that were coincidental (occurring on a single branch) or dispersed (occurring across multiple branches). In this illustration, the color of the dot indicates the tissues in which gene X’s expression changed. D Quantification of the coincidental expression changes along the branch leading to D. melanogaster. The height of each bar indicates the number of genes that have changed expression across the set of tissues indicated by the darkened/colored circles. The plot was truncated at the bin containing the overlap of the five tissues. E Quantification of the coincidental expression changes over all branches in the phylogeny. The height of each bar indicates the number of genes that have changed expression across the set of tissues indicated by the darkened/colored circles. The plot was truncated at the bin containing the overlap of the five tissues. F Summary of the distribution of the “coincidental index” for all expression changes. A coincidental index of 1 indicates that a gene has changed in expression in all tissues within a single branch (full coincidence), decreasing values indicating less coincidence. Location of source data for this figure can be found in “Source_data.xlsx”.