Table 1 Summary of the data set with 20,504 WES samples from the nine studies, sequenced using ten different capture kits across 14 sequencing centers
From: Human whole-exome genotype data for Alzheimer’s disease
Studies | Dataset ID in NIAGADS DSS | Sample count (After QC) | Sequencing platform | Capture kits used | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Agilent WES v3 capture region | Agilent WES v4 capture region | Agilent WES v5 capture region | Agilent WES v6 capture region | IDT xGen exome whole-exome research panel v1.0 w-custom spike-in baits | Illumina rapid capture exome (ICE) kit | Nimblegen VCRome sequencing w-custom spike-in baits | Nimblegen VCRome V2.1 | Roche SeqCap EZ exome probes v2.0 target enrichment probes | Roche SeqCap EZ exome probes v3.0 target enrichment probes | ||||
ADSP Discovery | snd000001 | 10657 | HiSeq 2000 /2500 | 4585 (59%) | 6072 (52%) | ||||||||
ADGC AA | snd000003 | 3157 | HiSeq 3000 | 3157 (41%) | |||||||||
Columbia WHICAP | snd000007 | 3861 | HiSeq 2000 /2500 | 3861 (21%) | |||||||||
Miami Families | snd000006 | 108 | HiSeq 2000 /2500 | 61 (74%) | 47 (89%) | ||||||||
CBD | snd000009 | 346 | HiSeq 2000 /2500 | 346 (100%) | |||||||||
PSP | snd000010 | 550 | HiSeq 2000 /2500 | 550 (100%) | |||||||||
Knight ADRC | snd000008 | 650 | HiSeq 4000 | 72 (86%) | 578 (33%) | ||||||||
FASe Families | snd000004 | 1100 | HiSeq 2000 /2500 | 714 (63%) | 164 (54%) | 222 (69%) | |||||||
Brkanac Families | snd000005 | 75 | HiSeq 2000 /2500 | 75 (77%) | |||||||||
