Fig. 1: Cryo-EM structures of MAP2 at the ribosomal tunnel exit. | Nature Communications

Fig. 1: Cryo-EM structures of MAP2 at the ribosomal tunnel exit.

From: Methionine aminopeptidase 2 and its autoproteolysis product have different binding sites on the ribosome

Fig. 1

a Domain organization of HsMAP1, compared to HsMAP2 and CtMAP2. Alphafold predictions of HsMAP1 and HsMAP2 are shown. The plain pita-bread fold is shown in gray. Structural features and insertions unique to MAP2 are highlighted in shades of green. Side- and top-view of (b) HsMAP2 and (c) CtMAP2 (shown in red) bound to the PTE and ES27L. The overviews on the left show the large 60S and small 40S subunit as well as the position of the tunnel exit. Tunnel exit proteins uL24, uL29, uL23, eL19, eL38 and parts of the 28S and 5.8S rRNA were built and are shown on the right side of the panels.

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