Table 1 Clinical and biological data of the 134 patients with mild to moderate CKD

From: WNT-dependent interaction between inflammatory fibroblasts and FOLR2+ macrophages promotes fibrosis in chronic kidney disease

Age (years)

46.5 (30.5–59.0)

Sex (male, n = )

84 (62.6%)

Ethnicity

Caucasian/white: n = 89; Afro-American: n = 23; Asian/Asian American: n = 15; Multi-racial: n = 4;

Diagnosis

MN: n = 43; MCD n = 27; FSGS: n = 36; IgAN n = 17; other: n = 11

HTN at biopsy (n = )

71 (53.0%)

eGFR at biopsy (mL/min/1.73 m2)

84.0 (65.0–104.9)

UPCR at biopsy (g/g)

3.8 (1.5–6.7)

Follow-up (months)

47.0 (30.3–55)

ESRD or decrease of 40% eGFR (n = )

31 (23%)

eGFR slope (mL/min/1.73 m2)

−1.62 (−4.6–1.1)

Fast progressors (n = )

36 (26.9%)

  1. MN membranous nephropathy, MCD minimal change disease, IgAN IgA nephropathy, HTN hypertension, eGFR estimated glomerular filtration rate, UPCR urinary protein-to-creatinine ratio, ESRD end-stage renal disease.
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