Fig. 6: The genetic programme of cKO IAHCs is different from that of WT IAHCs. | Nature Communications

Fig. 6: The genetic programme of cKO IAHCs is different from that of WT IAHCs.

From: Runx1+ vascular smooth muscle cells are essential for hematopoietic stem and progenitor cell development in vivo

Fig. 6: The genetic programme of cKO IAHCs is different from that of WT IAHCs.The alt text for this image may have been generated using AI.

a Barplot of fold enrichment for selected GO biological processes significantly overrepresented in genes significantly downregulated in cKO HSPCs compared to WT HSPCs. b Scatter plot of AUC (representing strength of downregulation) vs –log10(FDR), showing the top 25 significantly downregulated genes (red circles) in cKO HSPCs. Scatter plots of AUC vs –log10(FDR) highlighting downregulated genes associated with Gene Ontology (GO) biological processes. Red dots found above the dashed line (corresponding to FDR = 0.05) represent significantly downregulated genes (FDR < 0.05).

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