Fig. 1: Pharmacogenomics in American Indian and Alaska Native Communities.
From: Implementing community-engaged pharmacogenomics in Indigenous communities
We highlight key areas in pharmacogenomics (PGx) research and clinical implementation to bring about better health and well-being in AIAN communities: (1) Engaging the community (center), (2) increasing PGx knowledge of AIAN variation, (3) clinical implementation of PGx, and (4) inclusion of traditional knowledge and practices. Engaging the community is at the core, and this includes coordinating research with the tribal community, obtaining tribal approval, and encouraging tribal members to participate in data analysis, interpretation, and writing of results. Increasing knowledge related to PGx variants by including Indigenous peoples in basic and clinical research and the workforce, support for clinical implementation into healthcare, and including traditional knowledge and practices need to increase.
