Fig. 1: Previous syntheses of Tetrodotoxin and retrosynthetic analysis. | Nature Communications

Fig. 1: Previous syntheses of Tetrodotoxin and retrosynthetic analysis.

From: Total syntheses of Tetrodotoxin and 9-epiTetrodotoxin

Fig. 1

a Syntheses of TTX based on naturally occurring materials and retrosynthetic analysis of TTX. b Kishi’s first total synthesis of TTX. The oxygen atoms of TTX and 9-epiTTX are highlighted in red, and the nitrogen atoms are highlighted in blue. The TTX number is shown in pink.

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