Table 4 HLA-DRB1*0101-restricted CD4+ T cell epitopes identified in the literature (May 2021)
From: Human coronavirus OC43-elicited CD4+ T cells protect against SARS-CoV-2 in HLA transgenic mice
Protein | Start | End | Length | Sequence |
|---|---|---|---|---|
Spike | 530 | 544 | 15 | STDLIKNQCVNFNFN |
Envelope | 26 | 40 | 15 | FLLVTLAILTALRLC |
Membrane | 36 | 50 | 15 | QFAYANRNRFLYIIK |
66 | 80 | 15 | VLAAVYRINWITGGI | |
71 | 85 | 15 | YRINWITGGIAIAMA | |
86 | 100 | 15 | CLVGLMWLSYFIASF | |
91 | 105 | 15 | MWLSYFIASFRLFAR | |
116 | 130 | 15 | TNILLNVPLHGTILT | |
136 | 150 | 15 | SELVIGAVILRGHLR | |
146 | 160 | 15 | RGHLRIAGHHLGRCD | |
151 | 165 | 15 | IAGHHLGRCDIKDLP | |
161 | 175 | 15 | IKDLPKEITVATSRT | |
166 | 180 | 15 | KEITVATSRTLSYYK | |
176 | 190 | 15 | LSYYKLGASQRVAGD | |
191 | 205 | 15 | SGFAAYSRYRIGNYK | |
Nucleoprotein | 81 | 95 | 15 | DDQIGYYRRATRRIR |
86 | 100 | 15 | YYRRATRRIRGGDGK | |
126 | 140 | 15 | NKDGIIWVATEGALN | |
211 | 225 | 15 | AGNGGDAALALLLLD | |
216 | 230 | 15 | DAALALLLLDRLNQL | |
221 | 235 | 15 | LLLLDRLNQLESKMS | |
261 | 275 | 15 | KRTATKAYNVTQAFG | |
301 | 315 | 15 | WPQIAQFAPSASAFF | |
317 | 331 | 15 | MSRIGMEVTPSGTWL | |
326 | 340 | 15 | PSGTWLTYTGAIKLD | |
346 | 360 | 15 | FKDQVILLNKHIDAY | |
351 | 365 | 15 | ILLNKHIDAYKTFPP | |
ORF1ab | 5041 | 5055 | 15 | SHRFYRLANECAQVL |
5246 | 5260 | 15 | LMIERFVSLAIDAYP | |
ORF3a | 106 | 120 | 15 | LYLYALVYFLQSINF |
116 | 130 | 15 | QSINFVRIIMRLWLC | |
ORF8 | 36 | 50 | 15 | PCPIHFYSKWYIRVG |
41 | 55 | 15 | FYSKWYIRVGARKSA | |
76 | 90 | 15 | IGNYTVSCLPFTINC | |
86 | 100 | 15 | FTINCQEPKLGSLVV | |
96 | 110 | 15 | GSLVVRCSFYEDFLE | |
101 | 115 | 15 | RCSFYEDFLEYHDVR |
