Fig. 1: Identification of putative Acrs using structural features.
From: Structure-guided discovery of anti-CRISPR and anti-phage defense proteins

A Schematic depiction of pipeline used to identify Acr proteins. B AlphaFold2 model of newly identified Acr (AcrVA5Bsp, in red) superposed to the experimental structure of AcrVA5 (in blue). The TM score (0-1) is used to estimate the topological similarity of protein structures. TM scores > 0.6 are structurally similar.