Fig. 3: Known and putative Acrs sharing structural similarities with multiple Acrs. | Nature Communications

Fig. 3: Known and putative Acrs sharing structural similarities with multiple Acrs.

From: Structure-guided discovery of anti-CRISPR and anti-phage defense proteins

Fig. 3

A Pairwise structural comparison between all known Acr proteins. Acr pairs with TM score > 0.6 are considered to be structurally similar. B An example of AlphaFold2 model of AcrIE8 (in red) superposed to AcrIC7 (blue). C, D An example of a putative Acr protein (in blue) sharing structural similarities to both (C) AcrIC5, and (D) AcrIIC4.

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