Fig. 5: BxaP confers immunity likely through abortive infection.
From: Structure-guided discovery of anti-CRISPR and anti-phage defense proteins
A BxaP is incorporated in type 3 BREX defense systems. Examples of genomic loci containing BxaP (top) and homolog in bacterial genomes. Genome/MAG identifier is shown below each taxon. B Distribution of BxaP-containing BREX systems in MAGs. The top image shows HHpred predicted domains in BxaP. C Growth curves of BxaP-containing E. coli in comparison with control (empty vector) and mutant-BxaP under varying T4 phage concentrations. Experiments were conducted in triplicates, and error bars represent SEM. D T4 phage replication dynamics in empty vector, BxaP-mutant, and BxaP-containing cells. Experiments were conducted in triplicates and error bars represent SEM. Source data are provided as a Source Data file.
