Fig. 7: Lost Signaling Pathways in the Aging Myometrium.
From: Effect of aging on the human myometrium at single-cell resolution
CCC chord diagrams displaying signaling pathways active in the perimenopausal myometrium but lost during aging, including those related to A angiogenesis (HGF), B homeostasis and tissue repair (CALCR, PERIOSTIN), C contractility (ncWNT), D immune processes (IL10, CD22, CD48) and E nervous system regulation (NGF, L1CAM). Arrows between cell types show the direction of the interactions and follow the color code of cell types commonly detected in menopause. The relative thickness of each line depicts the expression-based strength of the interaction between cell types.
