Fig. 7: Increase in transgenic uterine size in estrus. | Nature Communications

Fig. 7: Increase in transgenic uterine size in estrus.

From: A common allele increases endometrial Wnt4 expression, with antagonistic implications for pregnancy, reproductive cancers, and endometriosis

Fig. 7

A TG shows an enlarged cross-sectional area of the uterine horn in estrus, excluding myometrium (P = 0.04; two tailed Student T-test, P = 0.074; Wilcoxon-Mann-Whitney rank sum test). As gene expression patterns indicated decreased proliferation, particularly in the luminal epithelium, differences in area likely correspond to increased secretion and luminal area along with possible oedema. Six independent samples of WT mice and 7 of TG mice were used. Boxplots show the median (central line) and interquartile range (50% of the data fall within the box), with the whiskers covering the range of data (Q1 or Q3 + 1.5IQR). B Two H&E-stained cross-sectional uterine samples of each genotype. Scale bar in each image measures 300 µm.

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