Fig. 1: Metagenomics-based profiles show taxonomic signatures associated with recurrence at 2 years (2Y-R) in two different time points. | Nature Communications

Fig. 1: Metagenomics-based profiles show taxonomic signatures associated with recurrence at 2 years (2Y-R) in two different time points.

From: Influence of microbiota-associated metabolic reprogramming on clinical outcome in patients with melanoma from the randomized adjuvant dendritic cell-based MIND-DC trial

Fig. 1: Metagenomics-based profiles show taxonomic signatures associated with recurrence at 2 years (2Y-R) in two different time points.

A, B Linear model coefficients for microbial SGBs associated either with 2y-R or 2y-noR, corrected for age, gender and treatment arm at baseline (A, T1 n = 86) or after 4 weeks of therapy start (B, T2 n = 83). Positive values indicate species-level genome bin (SGB) association with 2Y-R (orange), while negative values indicate a positive association for the corresponding SGB with 2Y-noR (blue). Only associations with p ≤ 0.05 are reported since no association has Benjamini-Hochberg Q < 0.2. Refer to Supplementary Data 1 for linear model coefficients (MaAsLin2, coefficient) for microbial SGBs after arcsine square root (arcsin-sqrt) transformation (AST). Source data are provided as a Source Data file.

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