Table 1 Baseline characteristics of study participants from Swedish exploration cohort and UK validation cohort
From: Disease clusters subsequent to anxiety and stress-related disorders and their genetic determinants
Exploration dataset derived from Swedish national registersa | Validation dataset derived from the UK Biobank | |||
|---|---|---|---|---|
Individuals with anxiety and stress-related disorders (N = 70,026) | Matched individualsb (N = 700,260) | Individuals with anxiety and stress-related disorders (N = 23,365) | Matched individualsb (N = 233,596) | |
Age at diagnosis in years, median (IQR) | 51 (45–60) | 51 (45–60) | 52 (46–59) | 52 (46–59) |
Follow-up time in years, median (IQR) | 7.1 (3.3–10.7) | 7.3 (3.5–10.8) | 13.5 (9.4–17.3) | 13.3 (9.4–17.3) |
Sex (%) | ||||
Male | 26,093 (37.3) | 260,930 (37.3) | 7631 (32.7) | 76,285 (32.7) |
Female | 43,933 (62.7) | 439,330 (62.7) | 15,734 (67.3) | 157,311 (67.3) |
Highest Education (%) | ||||
<9 y | 13,816 (19.7) | 130,074 (18.6) | 12,250 (52.4) | 116,528 (49.9) |
9–12 y | 33,516 (47.9) | 329,046 (47.0) | ||
>12 y | 22,694 (32.4) | 241,140 (34.4) | 6792 (29.1) | 79,987 (34.2) |
Missing | 4323 (18.5) | 37,081 (15.9) | ||
Income (%) | ||||
Lowest 20% | 1665 (2.3) | 14,917 (2.1) | 5046 (21.6) | 46,283 (19.8) |
Middle | 50,210 (71.7) | 445,510 (63.6) | 13,968 (59.8) | 139,967 (59.9) |
Highest 20% | 18,126 (25.9) | 238,475 (34.1) | 4314 (18.5) | 47,066 (20.2) |
Missing | 25 (0.1) | 1358 (0.2) | 37 (0.1) | 280 (0.1) |
