Table 2 The comparison of different glutarate synthetic pathways

From: RETRACTED ARTICLE: Systems engineering of Escherichia coli for high-level glutarate production from glucose

Categories

AMV

CAD

RAD

KED

KR

AMA

ΔrG’m (kJ/mol)*

–539.8

–122.5

–66.9

–110.0

–126.9

–384.7

MDF (kJ/mol)*

34.14

37.24

6.84

18.99

34.05

123.98

Reaction steps

4

5

5

5

6

3

Number of cofactors

1

2

3

3

3

1

Intermediates participation

1

2

0

0

0

0

  1. *Data was generated by eQuilibrator.
  2. AMV the 5-aminovalerate pathway, CAD the cadaverine pathway, RAD the reverse adipate degradation pathway, KED the-ketoglutarate carbon chain extension and decarboxylation pathway, KR the α-ketoglutarate reduction pathway, AMA the pathway designed in this study.