Table 2 Clade-specific variants for the North Wales sub-cluster

Position in EC958	EC958^a	Cluster^a	Change^b	Impact	Codon	Gene	Product
900,998	G	A	W = >stop	HIGH	159	nfsA	Oxygen-insensitive NADPH nitroreductase
1,052,210	G	T	G = > C	MODERATE	403	ycaQ	Uncharacterized protein
1,113,811	C	T	Syn	LOW	74	appB	Cytochrome bd-II ubiquinol oxidase subunit 2
1,842,716	T	C	S = > P	MODERATE	2	ydiS	Probable electron transfer flavoprotein-quinone oxidoreductase
2,372,060	G	A	Syn	LOW	413	gatZ	D-tagatose-1,6-bisphosphate aldolase subunit
2,405,414	CG	C	Deletion	MODIFIER
2,468,793	G	A	Syn	LOW	92	yeiR	Zinc-binding GTPase
2,485,972	A	G	Syn	LOW	302	yejM	Inner membrane protein
3,196,673	G	A	Syn	LOW	258	xanQ	Xanthine permease
4,706,103	C	G	W = > S	MODERATE	31	mdtN	Multidrug resistance protein
4,734,158	A	G	S = > P	MODERATE	205	basS	Sensor protein

^aEmboldened and italicised nucleotides are specific to sub-clade C2 EC958 and isolates within the North Wales sub-cluster, respectively
^bConsequence of SNP relative to EC958 (C2).
^bSynonymous change (Syn); non-synonymous changes to protein-coding genes are shown by single letter amino acid abbreviation (EC958 sequence on the left, SNP impact on right); blank lines indicate variant in intergenic region

Quick links

Search