Fig. 1: Design strategy for US-induced tandem catalysis to trigger robust SDT and CDT. | Nature Communications

Fig. 1: Design strategy for US-induced tandem catalysis to trigger robust SDT and CDT.

From: Ultrasound-activated piezo-hot carriers trigger tandem catalysis coordinating cuproptosis-like bacterial death against implant infections

Fig. 1

a Fabrication of CpBT nanoreactors and PH-CpBT bone scaffold. b Driven by US-activated tandem catalysis, CpBT nanoreactors can trigger cascade reactions between SDT and CDT. S. aureus was eradicated through cuproptosis-like death and cell oxidative stress mediated by ROS. c In an infected bone implant model, the PH-CpBT bone scaffold showed good antibacterial, angiogenesis, and osteogenesis multifunctionality in vivo, synergistically.

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