Table 3 Cross table indicating the number of genes whose expression colocalises in adipose/brain tissue with BMI

From: PheWAS-based clustering of Mendelian Randomisation instruments reveals distinct mechanism-specific causal effects between obesity and educational attainment

 

Cluster1

Cluster2

Cluster3

Cluster4

Cluster5

Cluster6

Adipose

9

9

14

3

6

5

Brain

3

3

4

1

2

4

Both

1

2

1

1

4

4

Neither

29

77

36

23

53

47

  1. The colocalisation exercise was performed at loci-defined BMI IVs falling into particular clusters. Colocalisation was defined as the posterior probability of both GWAS and eQTL being associated is ≥ 0.8 in either brain or adipose tissue or both.
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