Fig. 6: Gene imputation for IRI timecourse and independent validation of imputation.

A Cell-type-specific expression of the disease genes Nox4, Tarm1, Klhl3, and Frmpd4 across IRI timecourse as revealed by snRNA-seq. B Visualization of imputed gene expression and spatial distribution for Nox4, Tarm1, Klhl3, and Frmpd4. C Validation of Nox4 expression in kidney tissue across the IRI timecourse. Kidney section was costained with Nox4 (green), Havcr1 (red) and; Lotus Tetragonolobus Lectin (LTL, white).