Fig. 3: Substrate scope of BHMeHis1.8.
From: A non-canonical nucleophile unlocks a new mechanistic pathway in a designed enzyme
BHMeHis1.8 promotes the MBH reaction with a range of alkene and aldehyde coupling partners with high conversions to product and selectivities. X = CH2 or O, n = 0 or 1. Specific reaction conditions are presented in Supplementary Table 6. Source data are provided as a Source Data file.
