Fig. 2: Global interactome between human and Ece1-derived peptides.

a Bar chart showing total human interactors for each of the eight peptides with shared interactors displayed in the histograms as connected dots. b Interaction network of the Ece1 peptide-human ORFeome whereby each peptide is assigned with a different color: Ece1-I (red), Ece1-II (blue), Ece1-III (green), Ece1-IV (purple), Ece1-V (yellow), Ece1-VI (orange), Ece1-VII (brown), and Ece1-VIII (pink). Overlapped genes are centrally located in the diagram, and the noted genes were commonly shared among multiple peptides. c Circos plot involving the eight Ece1 peptides, whereby the outer ring (color-coded as in panel c) represents the genes interacting with each peptide, while the inner ring represents genes shared between two or more peptides (dark orange) or genes solely interacting with the individual peptide (light orange). Purple lines connect the peptides that share the interaction genes and blue lines connect genes belonging to the same functional group. d Stacked bar graph representing the relative abundances of subcellular localization involving human interactors with each Ece1 peptide. The ‘Others’ category includes: Actin filaments, Centrosome, Microtubules, Focal Adhesion Sites, Intermediate Filaments, Peroxisomes, Microtubule Ends, Cell Junctions, Midbody Ring, Endosomes, Lysosomes, Centriolar Satellite, and Cytokinetic Bridge.