Fig. 8: GPR109A-G-protein interacting residues.

a–e Key interactions between Gαo residues and residues of the cytoplasmic core of GPR109A. Black dotted line represents the H-bond. f–j List of GPR109A residues interacting with Gαo in niacin, acipimox, MK6892, GSK256073, and MMF bound structures.