Fig. 3: TcsH-CROP unit-VI recognizes TMPRSS2SPD. | Nature Communications

Fig. 3: TcsH-CROP unit-VI recognizes TMPRSS2SPD.

From: Molecular basis of TMPRSS2 recognition by Paeniclostridium sordellii hemorrhagic toxin

Fig. 3: TcsH-CROP unit-VI recognizes TMPRSS2SPD.

a Hydrophobicity of the TcsH-TMPRSS2 interface. The SRs and LRs of TcsH and surface loops of TMPRSS2 that participate in the interactions are colored and labeled as follows: LR: pink; SR: dark blue; LE: magenta; LA: yellow; LB: orange; L2: purple; L3: brown; (b) The top view of the complex shows that TMPRSS2SPD interacts with TcsH through five loops. c–e Close-up views of the TcsH-TMPRSS2 interface with interacting side chains shown as sticks and colored as shown in (a). Hydrogen bonds are shown as blue dotted lines.

Back to article page