Table 1 Characteristics of study participants by population group and inclusion in analysis after filtering

From: Genomic malaria surveillance of antenatal care users detects reduced transmission following elimination interventions in Mozambique

 

First ANC users

Children 2–10 years

All

Passed filtering

Filtered out

All

Passed filtering

Filtered out

Total number N (%)

378 (100)

289 (76.5)

89 (23.5)

180 (100)

93 (51.7)

87 (48.3)

Age median years (IQR)

21 (18;27)

21 (18;27)

22 (19;29)

4.0 (3.0;6.3)

4.6 (3.0;6.8)

4.0 (3.0;6.0)

Parasite density GM parasite/µL (GSD)

86.6 (16.9)

191 (12.4)

6.6 (9.0)

41.1 (18.7)

154 (12.8)

7.1 (11.7)

Year

 2015–2016, n (%)

0

0

0

93 (100)

60 (64.5)

33 (35.5)

 2017, n (%)

210 (100)

166 (79.0)

44 (21.0)

21 (100)

4 (19.0)

17 (81.0)

 2018–2019, n (%)

168 (100)

123 (73.2)

45 (26.8)

66 (100)

29 (43.9)

37 (56.1)

Area

 Magude, n (%)

155 (100)

120 (77.4)

35 (22.6)

101 (100)

47 (46.5)

54 (53.5)

 Manhiça, n (%)

87 (100)

64 (73.6)

23 (26.4)

71 (100)

42 (59.2)

29 (40.8)

 Ilha Josina, n (%)

136 (100)

105 (77.2)

31 (22.8)

8 (100)

4 (50.0)

4 (50.0)

Season

 Dry, n (%)

233 (100)

182 (78.1)

51 (21.9)

180 (100)

93 (51.7)

87 (48.3)

 Rainy, n (%)

145 (100)

107 (73.8)

38 (26.2)

0 (0)

0 (0)

0 (0)

HIV

 Negative, n (%)

291 (100)

221 (75.9)

70 (24.1)

NA

NA

NA

 Positive, n (%)

87 (100)

68 (78.2)

19 (21.8)

NA

NA

NA

Gravidity

 Primigravid, n (%)

143 (100)

117 (81.9)

26 (18.2)

NA

NA

NA

 Multigravid, n (%)

235 (100)

172 (73.2)

63 (26.8)

NA

NA

NA

Sequencing coverage

Reads/sample, GM (GSD)

6.8 × 104 (27.2)

3.2 × 105 (4.0)

470 (15.5)

8.5 × 103 (100.0)

4.8 × 105 (5.3)

115 (8.7)

N loci* covered/sample, median (IQR)

221 (173;224)

223 (209;225)

75 (25;128)

170 (41;214)

213 (208;224)

40 (13.5;81)

  1. All available samples were sequenced. Those that did not pass the filtering criteria were excluded, while the remaining samples were included in the analysis. Population groups are (1) pregnant women attending their first antenatal care (ANC) visit, and (2) children aged 2-10 years sampled in population-representative household surveys.
  2. N number, IQR interquartile range, GM geometric mean, GSD geometric standard deviation, NA not applicable. *On average, each locus was covered by 1.4 million reads and 462 samples.