Fig. 3: Proteomic analysis of differences in peripheral blood mononuclear cells between BA.2-breakthrough infection (BTI)-6m and control groups.

a Tree cluster diagram depicts sample separation between the two groups. b Volcanic map indicates differential proteins between the two groups. c The heat map shows the differential proteins in the control and BA.2-BTI-6m groups. d Bubble chart displays the biological processes and functions of the enriched differentially expressed proteins. e Sankey diagram shows relationships between upregulated proteins and enriched biological processes. f Sankey diagram shows relationships between downregulated proteins and enriched biological processes.