Fig. 5: Prediction of G4 binders vs. non-binders based on eCLIP-identified RBP targets. | Nature Communications

Fig. 5: Prediction of G4 binders vs. non-binders based on eCLIP-identified RBP targets.

From: Predicting nuclear G-quadruplex RNA-binding proteins with roles in transcription and phase separation

Fig. 5

a Enhanced differentiation of G4 binders from non-binders is associated with rising G4 RNA propensity scores. b The differentiation intensifies with increased cleverMACHINE confidence levels. For both analyses, ‘the G4-binding to non-G4-binding protein ratio is determined’ by the count of G4s associated with each category. Proteins predicted to bind folded G4 are written in bold. See also Supplementary Data 8.

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