Fig. 7: Working model of auxin signaling involving miR408-5p regulation in rice.
From: Switching action modes of miR408-5p mediates auxin signaling in rice

Compared with that in low auxin environment, rice in high auxin condition represses miR156 and promotes more association of IPA1 with MIR408 cis-element to trigger higher accumulations of mature miR408-5p, thereby leading to switch miR408-5p action from translation repression to mRNA cleavage. In addition to a higher contribution from canonical receptor-mediated auxin signaling, more robust regulation of IAA30 by miR408-5p in rice through mRNA cleavage results in an enhanced auxin response in a high than in a low auxin environment.