Fig. 2: Comparison of metabolic phenotypes in fathers and female offspring.

Note, offspring are plotted against diet composition of fathers. a, d Fasting blood glucose (mg/dL) measured during glucose tolerance test at 18 weeks of age, b, e weight (g) of subcutaneous white adipose tissue deposits (combined weight of left and right deposit) measured at cull, c, f weight (g) of interscapular brown adipose tissue (combined weight of left and right deposit) measured at cull. An effect of dietary macronutrient content on the outcome of interest was inferred, when the non-null statistical model (i.e., that fitting an effect of diet) had an Akaike Information Criterion (AIC) more than two points lower than the null model (i.e., △AIC < −2). a F0 Fasting Glucose △AIC = −2.2, n = 60, b F0 Subcutaneous fat △AIC = −15.15, n = 60, c F0 Brown fat △AIC = −16.63, n = 60, d F1 Fasting Glucose △AIC = −3.51, n = 50, e F1 Subcutaneous fat △AIC = −6.67, n = 50, f F1 Brown fat △AIC = −2.51, n = 50. Full model coefficients are given in Supp Table 2. Source data for fathers (a–c) are provided in Source Data File 1, and for female offspring (d–f) in Source Data File 2. Created with BioRender.com.